A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 9/00 (2006.01)
Patent
CA 2450366
The present invention is directed to a method and system for delivering a drug into the systemic circulation. The method comprises establishing a drug depot in a patient's skin and/or sub-skin tissues by applying a transdermal drug delivery system on the patients skin, for a predetermined time so that a drug depot is formed in said user's skin and/or sub-skin tissues. A heating source is placed proximate to the skin area to rapidly release a bolus of the drug from the depot into the systemic circulation when there is a need to rapidly increase the drug's concentrations in the systemic circulation.
La présente invention concerne un procédé et un système permettant de faire pénétrer dans la circulation systémique un médicament. Le procédé fait créer un dépôt de médicament dans les tissus cutanés et/ou sous-cutanés du patient. A cet effet, on applique sur la peau des patients un système d'administration percutané que l'on laisse un certain temps de façon à constituer un dépôt médicamenteux dans les tissus cutanés et/ou sous-cutanés de l'utilisateur. Une source de chaleur est placée à proximité de la zone cutanée de façon, à partir du dépôt, à libérer rapidement dans la circulation systémique un bolus de médicament dès lors qu'il est devenu indispensable d'augmenter rapidement la concentration du médicament dans la circulation systémique.
Hull Wade
Rigby Larry
Zhang Jie
Cassan Maclean
Zars Inc.
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