Controlled porosity expanded polytetrafluoroethylene...

A - Human Necessities – 61 – L

Patent

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A61L 27/00 (2006.01) A61F 2/06 (2006.01) A61L 27/16 (2006.01) A61L 27/56 (2006.01) B01D 69/08 (2006.01) B29C 47/00 (2006.01) B29C 55/00 (2006.01) B29D 23/00 (2006.01) C08J 9/28 (2006.01) C12M 1/00 (2006.01) C12M 3/00 (2006.01)

Patent

CA 2131902

A method of forming porous articles with a varying pore distribution by extrusion from a billet with varying lubricant distribution. A single-polymer polytetrafluoroethylene is extruded and then stretched and sintered to provide a differential porous PTFE structure composed of fibers and nodes connected to one another by these fibers. The microfibrous structure has a portion within the cross section that possesses a different pore size, accompanied by a different node and fiber geometry, than adjacent areas within the cross section. A tube (10), having elongate nodes (12), fibrils (14), an inner surface (16) and an outer surface (18), of an expanded, porous fluoropolymer material, which is useful as a vascular graft, is formed. In a vascular graft, the pores taper inwardly, providing a fluid-tight lumen wall structure that prevents leakage, yet promotes cellular growth and natural tissue generation. A node structure of radially-oriented plates provides flexibility, suture strength, and enhanced protection against collapse.

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