Controlled porosity osmotic pump

A - Human Necessities – 61 – K

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128/104, 167/153

A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61M 31/00 (2006.01)

Patent

CA 1266827

1628M/0786A IX-112IA TITLE OF THE INVENTION CONTROLLED POROSITY OSMOTIC PUMP ABSTRACT OF THE DISCLOSURE The instant invention is directed to an osmotic pump comprising: (A) at least one active agent surrounded by (B) a water insoluble wall, having a fluid permeability of 6.96 x 10-18 to 6.96 x 10-14 cm 3 sec/g and a reflection coefficient of less than 1, prepared from: (i) a polymer permeable to water but impermeable to solute and (ii) 0.1 to 60% by weight, based on the total weight of (i) and (ii) , of at least one pH insensitive pore forming additive dispersed throughout said wall.

483594

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