A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
128/104, 167/153
A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61M 31/00 (2006.01)
Patent
CA 1266827
1628M/0786A IX-112IA TITLE OF THE INVENTION CONTROLLED POROSITY OSMOTIC PUMP ABSTRACT OF THE DISCLOSURE The instant invention is directed to an osmotic pump comprising: (A) at least one active agent surrounded by (B) a water insoluble wall, having a fluid permeability of 6.96 x 10-18 to 6.96 x 10-14 cm 3 sec/g and a reflection coefficient of less than 1, prepared from: (i) a polymer permeable to water but impermeable to solute and (ii) 0.1 to 60% by weight, based on the total weight of (i) and (ii) , of at least one pH insensitive pore forming additive dispersed throughout said wall.
483594
Himmelstein Kenneth J.
Rork Gerald S.
Zentner Gaylen M.
Goudreau Gage Dubuc
Merck & Co. Inc.
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