Controlled-release clozapine compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/14 (2006.01) A61P 25/18 (2006.01) A61K 31/551 (2006.01)

Patent

CA 2757979

A composition for delivery of a drug is disclosed. The composition has a semipermeable coating, particles of clozapine having an effective average particle size of less than or about 2 µm and at least one surface stabilizer adsorbed on the surface of the clozapine particles, and a solubilizing agent.

L'invention porte sur une composition d'administration d'un médicament. La composition comporte un revêtement semi-perméable, des particules de clozapine présentant une dimension de particule moyenne efficace inférieure ou égale à 2 µm et au moins un stabilisant de surface absorbé sur la surface des particules de clozapine et un agent de solubilisation.

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