Controlled release combination of carbidopa/levodopa

Details Controlled release combination of carbidopa/levodopa Controlled release combination of carbidopa/levodopa

A - Human Necessities

61

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167/260

A61K 31/195 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/26 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1318602

6342S/5351A 17228IB TITLE OF THE INVENTION CONTROLLED RELEASE COMBINATION OF CARBIDOPA/LEVODOPA ABSTRACT OF THE INVENTION A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists of the two drugs uniformly dispersed in a polymer vehicle at a concentration that is greater than the solubility of either drug in the polymer. Treatment of parkinsonism with the controlled release formulation provides several advantages over treatment with the standard carbidopa/levodopa combinations presently employed.

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