Controlled release composition

Details Controlled release composition Controlled release composition

A - Human Necessities

61

K

A61K 47/30 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 31/4164 (2006.01) A61K 31/5513 (2006.01)

Patent

CA 2329574

The present invention provides a composition comprising a sustained release layer and a fast release layer. The sustained release layer comprises a water- soluble polymer and a first pharmaceutically active agent. The fast release layer comprises a matrix forming agent and a second pharmaceutically active agent. Generally, the composition provides fast and sustained (or controlled) release of a pharmaceutically active agent for at least 6 hours and preferably for at least 1 to 3 days. The composition may be incorporated into a dosage unit form, such as a vaginal insert. Methods of preparing the composition are also provided.

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