Controlled release compositions of agents that reduce...

Details Controlled release compositions of agents that reduce... Controlled release compositions of agents that reduce...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 38/17 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01) A61L 27/22 (2006.01) A61P 7/00 (2006.01) A61P 9/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2728213

Provided are prophylactic and therapeutic methods of treatment of subjects for the purpose of inhibiting vaso-oc-clusive events, including embolism, by administering agents, including anagrelide and anagrelide derivatives, which reduce the number of circulating platelets to low normal or to below normal levels. Methods and pharmaceutical preparations comprising such agents are provided.

L'invention concerne des procédés prophylactiques et thérapeutiques de traitement de sujets dans le but d'inhiber des évènements vaso-occlusifs, y compris un embolisme, par administration d'agents, y compris de l'anagrélide et des dérivés d'anagrélide, qui réduisent le nombre de plaquettes en circulation à des niveaux normaux faibles ou inférieurs à la normale. L'invention concerne également des procédés et des préparations pharmaceutiques comprenant de tels agents.

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