Controlled-release compositions of betahistine

Details Controlled-release compositions of betahistine Controlled-release compositions of betahistine

A - Human Necessities

61

K

A61K 9/26 (2006.01) A61K 9/16 (2006.01) A61K 31/4402 (2006.01) A61P 1/08 (2006.01)

Patent

CA 2364226

Oral solid controlled-release formulations of betahistine, obtained subjecting the active ingredient to a melt-granulation process with a fatty compound and then mixing the obtained granulate with a hydrophilic polymer and with conventional excipients.

L'invention concerne des formulations de bétahistine orales solides à libération prolongée, que l'on obtient en soumettant le principe actif à un processus de granulation à chaud avec un composé gras, puis en mélangeant la substance granuleuse ainsi obtenue à un polymère hydrophile et à des excipients traditionnels.

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