Controlled release delivery system for nasal application of...

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2664427

This invention relates to a galenical gel formulation for nasal administration of neurotransmitters such as dopamine. The special lipophilic or partly lipophilic system of the invention leads to high bioavailability of the active ingredient in plasma and brain caused by sustained serum levels and/or direct or partly direct transport from nose to the brain.

Cette invention concerne une formulation de gel galénique pour administration nasale de neurotransmetteurs tels que la dopamine. Le système spécial lipophile ou partiellement lipophile de l'invention conduit à une biodisponibilité élevée de l'ingrédient actif dans le plasma et le cerveau provoquée par des taux de sérum entretenus et/ou un transport direct ou partiellement direct du nez au cerveau.

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