Controlled-release dosage forms comprising zolpidem or a...

Details Controlled-release dosage forms comprising zolpidem or a... Controlled-release dosage forms comprising zolpidem or a...

A - Human Necessities

61

K

A61K 31/437 (2006.01) A61K 9/24 (2006.01) A61K 9/52 (2006.01)

Patent

CA 2391983

The present invention relates to controlled-release dosage forms of zolpidem or salts thereof adapted to release zolpidem over a predetermined time period, according to a biphasic profile of dissolution, where the first phase is an immediate release phase and the second phase is a prolonged release phase and particular embodiments thereof intended to avoid abuse.

La présente invention concerne des formes posologiques à libération régulée de zolpidem ou de ses sels, conçues pour libérer du zolpidem pendant une certaine période de temps, selon un profil biphasique de dissolution. La première phase est une phase à libération immédiate, la seconde phase étant une phase à libération prolongée. En outre, cette invention concerne des modes de réalisations particuliers prévus pour empêcher l'abus de ce type de substance.

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