Controlled release dosage forms having a defined water content

Details Controlled release dosage forms having a defined water content Controlled release dosage forms having a defined water content

A - Human Necessities

61

K

167/220

A61K 31/52 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01)

Patent

CA 1323834

ABSTRACT A controlled release, solid, oral dosage form containing a 3-alkylxanthine, preferably theophylline, at least one hydrophilic or hydrophobic polymer, at least one wax having a melting point between 25° and 90°C and between 3% and 10% (by weight) water. Preferably the dosage form is a tablet and the water content is between 9% and 9% (by weight). The amount of water present in the dosage form determines the rate of release of the 3-alkylxanthine.

600949

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