Controlled release formulations using intelligent polymers

Details Controlled release formulations using intelligent polymers Controlled release formulations using intelligent polymers

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/35 (2006.01)

Patent

CA 2732093

A controlled release pharmaceutical composition comprises (a) topiramate or a pharmaceutically acceptable salt thereof, (b) a first intelligent polymer component; and (c) a second intelligent polymer component having opposite wettability characteristics to the first intelligent polymer component. The polymer components are effective for controlled release of the pharmaceutically active substance from the composition.

L'invention porte sur une composition pharmaceutique à libération contrôlée qui comprend (a) du topiramate ou un sel pharmaceutiquement acceptable de celui-ci, (b) un premier composant polymère intelligent; et (c) un second composant polymère intelligent ayant des caractéristiques de mouillabilité opposées au premier composant polymère intelligent. Les composants polymères sont efficaces pour une libération contrôlée de la substance pharmaceutiquement active à partir de la composition.

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