Controlled release granules comprising porous silica core

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/24 (2006.01) A61K 9/14 (2006.01) A61K 9/50 (2006.01) A61K 9/54 (2006.01) A61K 9/62 (2006.01) A61K 31/522 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2438438

The present invention relates to controlled release granules for medical use comprising a drug loaded porous silica particle, and at least one layer of a controlled release coating material, characterized in that the drug loaded porous silica core is prepared by immersing dry porous silica particles with a solution, suspension or emulsion comprising at least one pharmacologically active drug and the resulting wet drug loaded porous silica core is subsequently dried again. Furthermore, the invention concerns a method for preparing the controlled release composition.

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