Controlled release microencapsulated ngf formulation

Details Controlled release microencapsulated ngf formulation Controlled release microencapsulated ngf formulation

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 9/50 (2006.01) A61P 25/02 (2006.01)

Patent

CA 2293575

NGF microencapsulation compositions having controlled release characteristics, preferably with increased stability, for the NGF component, particularly human recombinant NGF ("rhNGF") are provided that yield enhanced stability of NGF for use in promoting nerve cell growth, repair, survival, differentiation, maturation or function. Methods for making and using such compositions are also provided.

Cette invention se rapporte à des compositions de microencapsulation du facteur de croissance du tissu nerveux (NGF), ayant des caractéristiques de libération régulée, de préférence avec une stabilité accrue, pour le composant NGF, en particulier le NGF recombiné humain (rhNGF), ces compositions permettant de produire une stabilité accrue du NGF pour qu'il puisse servir à stimuler la croissance, la réparation, la survie, la différenciation, la maturation ou la fonction des cellules nerveuses. Des procédés de fabrication et d'utilisation de ces compositions sont également présentées.

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