Controlled release modifying complex and pharmaceutical...

A - Human Necessities – 61 – K

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A61K 9/52 (2006.01) A61K 9/22 (2006.01) A61K 9/30 (2006.01) A61K 9/32 (2006.01) A61K 9/34 (2006.01) A61K 9/36 (2006.01) A61K 9/56 (2006.01)

Patent

CA 2493899

Disclosed is a controlled release modifying complex for solid suitable comprises modifying excipients. The release modifying an auxiliary release thereof, wherein modifying agents effect and ingredient.oral controlled release pharmaceutical for an once-a-day administration. The active pharmaceutical ingredient, compositions composition a release complex and other required pharmaceutically acceptable release modifying complex comprises a primary agent, a secondary release modifying agent and modifying agent or varying combinations said primary, secondary and auxiliary release are present in amounts that synergistically extend the release of active pharmaceutical ingredient.

Complexe modifiant la libération contrôlée pour compositions pharmaceutiques solides orales à libération contrôlée adaptées pour l'administration en une seule dose quotidienne. Ladite composition contient un ingrédient pharmaceutique actif, un complexe modifiant la libération et d'autres excipients requis acceptables sur le plan pharmaceutique. Ledit complexe de modification de libération comporte un agent de modification de libération primaire, un agent de modification de libération secondaire et un agent de modification de libération auxiliaire ou des combinaisons variables desdits agents. Lesdits agents primaire, secondaire et auxiliaire sont présents dans des quantités possédant un effet synergique et prolongent la libération de l'ingrédient pharmaceutique actif.

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