Controlled release naproxen and naproxen sodium tablets

A - Human Necessities – 61 – K

Patent

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167/161

A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1204671

23940 ABSTRACT OF THE DISCLOSURE A controlled release tablet for once-daily oral administration of about 500-1200 mg of naproxen or naproxen sodium, said tablet being a homogeneous matrix comprising about 4-9 weight percent of hydroxypropyl- methylcellulose having a number average molecular weight in the range of from about 80,000 to about 130,000, about 81-96 weight percent naproxen or naproxen sodium, 0.1 to about 2 weight percent of a pharmaceutically acceptable lubricating agent, and 0 to about 8 weight percent of other pharmaceutically acceptable excipients.

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