Controlled-release of an active substance into a high fat...

Details Controlled-release of an active substance into a high fat... Controlled-release of an active substance into a high fat...

A - Human Necessities

61

K

A61K 9/36 (2006.01) A61K 9/00 (2006.01) A61K 9/28 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/495 (2006.01) A61K 31/4985 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2508722

A controlled release delivery composition which can be administered to a high fat use environment such as the human gastrointestinal tract following a high fat meal. The delivery composition is embodied as a core surrounded by an asymmetric polymeric membrane. In a preferred embodiment, the asymmetric polymeric membrane is cellulose acetate.

La présente invention a trait une composition d'administration à libération contrôlée qui peut être administrée à un milieu à haute teneur en graisse tel que la voie gastro-intestinale humaine suite à un repas à forte teneur lipidique. La composition d'administration est constitué d'un noyau entouré d'une membrane en polymère asymétrique. Dans un mode de réalisation préféré, la membrane en polymère asymétrique est de l'acétate de cellulose.

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