Controlled release of biological entities

A - Human Necessities – 61 – K

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Details

A61K 9/22 (2006.01) A61K 38/00 (2006.01) B01J 2/08 (2006.01)

Patent

CA 2591344

A process is provided for releasably encapsulating a biological entity. The process comprise combining a solution of a surfactant in a non-polar solvent with a precursor material and the biological entity to form an emulsion. The emulsion comprises a polar phase dispersed in a non- polar phase, wherein the polar phase comprises the biological entity. The particles comprising the biological entity are then formed from the polar phase.

La présente invention propose un procédé d'encapsulation d'une entité biologique pour sa libération ultérieure. Le procédé comprend la combinaison d'une solution d'un agent tensioactif dans un solvant non polaire avec une substance précurseur et l'entité biologique afin de former une émulsion. L'émulsion comprend une phase polaire dispersée dans une phase non polaire, la phase polaire comprenant l'entité biologique. Les particules qui constituent l'entité biologique sont ensuite formées à partir de la phase polaire.

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