Controlled release pharmaceutical compositions from...

Details Controlled release pharmaceutical compositions from... Controlled release pharmaceutical compositions from...

A - Human Necessities

61

K

167/168

A61K 9/26 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2025714

CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FROM SPHERICAL GRANULES IN TABLETTED ORAL DOSAGE UNIT FORM ABSTRACT OF THE INVENTION A controlled release pharmaceutical composition in oral dosage unit form comprising a tablet comprising a therapeutically effective number of active spherical granules comprising an effective amount of active medicament, a pharmaceutically acceptable normally solid diluent adapted to form a diffusible matrix for the active medicament and an optional pharmaceutically acceptable excipient; and a number of compressible spherical granules comprising a mono- or disaccharide, an optional pharmaceutical acceptable normally solid diluent adapted to form a diffusible matrix, an optional active medicament and/or an optional pharmaceutically acceptable excipient wherein the average comprehensive yield of the compressible spherical granules is less than the average compressible yield of the active spherical granules is provided. A method for the preparation and for the administration of the above defined composition is provided as well.

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