Controlled release pharmaceutical dosage forms of a...

Details Controlled release pharmaceutical dosage forms of a... Controlled release pharmaceutical dosage forms of a...

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 9/00 (2006.01) A61K 31/4706 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01)

Patent

CA 2473991

The present invention relates to controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor, (CETPI) methods of using and methods of making same. In particular, it relates to a controlled release form of the CETPI [2R,4S] 4-[(3,5-bis-trifluoromethyl-benzyl)- methodyycarbonyl-amino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1- carboxylic acid ethyl ester.

L'invention porte sur une forme posologique à libération contrôlée d'une protéine inhibant le transfert du cholestéryle ester (CEPTI), sur ses procédés de fabrication et d'utilisation, et en particulier sur une forme à libération contrôlée de CEPTI, ester de l'acide [2R,4S] 4-[(3,5-bis-trifluorométhyl-benzyl)-méthodyycarbonyl-amino]-2-éthyl-6-trifluorométhyl-3,4-dihydro-2H-quinoline-1-carboxylique.

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