Controlled-release pharmaceutical formulation

Details Controlled-release pharmaceutical formulation Controlled-release pharmaceutical formulation

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 31/18 (2006.01) A61P 13/08 (2006.01)

Patent

CA 2547586

In the present invention, a new pharmaceutical formulation with controlled release of the freely water soluble low-dose active substance used for at the most once daily administration is disclosed. The active substance is maintained at a suitable therapeutic concentration in the blood throughout at least a 24 hour period independent of the physiological pH value to which the pharmaceutical formulation is exposed.

L'invention concerne une nouvelle formulation pharmaceutique à libération contrôlée de la substance active à faible dose facilement soluble dans l'eau utilisée en une administration quotidienne au maximum. Ladite substance active est conservée en concentration thérapeutique appropriée dans le sang pendant au moins 24 heures indépendamment de la valeur du pH physiologique à laquelle la formulation pharmaceutique est exposée.

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