Controlled-release pharmaceutical formulation

Details Controlled-release pharmaceutical formulation Controlled-release pharmaceutical formulation

A - Human Necessities

61

K

A61K 31/137 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61P 25/00 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2702664

A pharmaceutical formulation comprising desvenlafaxine having an MMD of between about 5µm and about 100µm, or a pharmaceutically acceptable salt thereof, and at least one matrix rate- controlling pharmaceutically acceptable polymer, solid unit dosage form containing it, methods for preparing such a formulation and for its use to treat depression and related disorders and diseases.

L'invention porte sur une formulation pharmaceutique comprenant de la desvenlafaxine ayant un diamètre moyen massique compris entre environ 5 µm et environ 100 µm; ou sur son sel pharmaceutiquement acceptable, et sur au moins une matrice polymère pharmaceutiquement acceptable de régulation de la vitesse, sur une forme posologique unitaire solide la contenant, sur des procédés pour préparer une telle formulation et l'utiliser dans le traitement de la dépression, de troubles et maladies associés.

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