Controlled release pharmaceutical preparation

Details Controlled release pharmaceutical preparation Controlled release pharmaceutical preparation

A - Human Necessities

61

K

A61K 47/38 (2006.01) A61K 9/28 (2006.01) A61K 9/32 (2006.01) A61K 9/36 (2006.01) A61K 9/50 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2045358

A controlled release pharmaceutical preparation comprising a core containing a medicinal compound and a coating layer containing a water-repellent salt and a water-insoluble and slightly water-permeable acrylic polymer having trimethylammoniumethyl group. Said preparation releases a medicinal compound in a sigmoid type dissolution pattern irrespective of the PH of a dissolution medium.

Préparation pharmaceutique à libération lente comprenant un noyau contenant un composé médicinal et un enrobage contenant un sel hydrofuge et un polymère acrylique non soluble dans l'eau et légèrement perméable à l'eau comportant un groupement triméthylammoniuméthyl. La préparation en question libère un composé médicinal selon un modèle de dissolution sigmoïde sans égard au pH du milieu de dissolution.

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