A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/20 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2468703
The present invention is directed to an improved system for controlled release of a bone growth promoting compound and to a flowable composition for its formation. The flowable composition is composed of a bone growth promoting compound, a thermoplastic polymer and an organic solvent. The flowable composition is capable of forming a biodegradable and/or bioerodible microporous, solid polymer matrix. The matrix is useful as an implant in patients (humans and animals) for delivery of a bone growth promoting compound to certain tissues.
L'invention concerne un système amélioré de libération contrôlée d'un composé stimulant la formation osseuse, et une composition fluide permettant de former ce système. La composition fluide comprend un composé stimulant la formation osseuse, un polymère thermoplastique et un solvant organique. Cette composition fluide permet de former une matrice polymère solide microporeuse biodégradable et/ou bio-érodable. Utilisée en tant qu'implant chez un patient (humain ou animal), cette matrice permet l'administration d'un composé stimulant la formation osseuse à certains tissus.
Dumont Francis
Dunn Richard Lee
Jeffers Scott Alexander
Korsmeyer Richard Wilker
Li Mei
Pfizer Inc.
Torys Llp
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