A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/24 (2006.01) A61K 9/16 (2006.01) A61K 47/30 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2176933
A controlled release preparation comprises am ionic polymer matrix loaded with an active compound, particularly a pharmaceutically active compound such as doxorubicine or other cytotoxic or cytostatic drug, the active compound being complexed with a complexing agent such as a metal ion to modify the release of the active compound from the polymer matrix. The ionic polymer matrix may be provided in the form of microspheres, such as microspheres of cross-linked albumin/dextran sulphate.
Préparation à libération régulée comportant une matrice polymère ionique chargée d'un composé actif, et notamment d'un composé pharmaceutiquement actif tel que la doxorubicine ou un autre médicament cytotoxique ou cytostatique, ce composé actif étant complexé par un agent complexant tel qu'un ion métallique de manière à modifier la libération du composé actif à partir de la matrice polymère. La matrice polymère ionique peut se présenter sous la forme de microsphères telles que des microsphères en sulfate de dextrane/albumine réticulé.
Chen Yan
Gray Bruce Nathaniel
Ridout & Maybee Llp
Sirtex Medical Limited
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