Controlled release preparation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/52 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/22 (2006.01) A61K 31/4439 (2006.01)

Patent

CA 2499574

A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient.

L'invention concerne une préparation à libération contrôlée dans laquelle un ingrédient actif est libéré de manière contrôlée pendant une durée prolongée en restant dans le tractus gastro-intestinal ou en migrant lentement dans ce dernier. Cette préparation peut se présenter sous la forme d'une capsule comprenant des tablettes, des granules ou des granules fins, lesquels permettent la libération contrôlée de l'ingrédient actif, cette capsule comprenant également un polymère gélifiant. Ces tablettes, granules ou granules fins possèdent une couche de revêtement à libération contrôlée formée sur une particule centrale contenant un ingrédient actif.

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