Controlled release preparation containing cilostazol and...

Details Controlled release preparation containing cilostazol and... Controlled release preparation containing cilostazol and...

A - Human Necessities

61

K

A61K 9/10 (2006.01)

Patent

CA 2678482

A controlled release preparation which comprises particles containing cilostazol or its pharmaceutically acceptable salt dispersed in a solubilizing agent and an erodible material encasing said particles which is capable of forming a hydrogel, can maintain a constant level of cilostazol in the blood through its slow release during its prolonged residence time in the stomach and intestines, thereby minimizing adverse effects caused by rapid release of the drug or solubilizing agent.

Préparation à libération contrôlée contenant des particules contenant elles-mêmes du cilostazol ou un sel de qualité pharmaceutique de cette susbstance, dispersée dans un agent solubilisant et une matière érodable renfermant lesdites particules. Cette préparation peut former un hydrogel et maintenir un niveau constant de cilostazol dans le sang grâce à sa libération lente pendant un temps de séjour prolongé dans l'estomac et les intestins, ce qui atténue les effets contraires dus à une libération rapide du médicament ou de l'agent solubilisant.

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