A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 9/36 (2006.01) A61K 31/47 (2006.01) A61K 47/34 (2006.01)
Patent
CA 2678535
The present invention relates to a controlled-release formulation comprising cilostazol and a method for preparing said formultion. The inventive controlled-release formulation comprising cilostazol or a pharmaceutically acceptable salt thereof, a solubilizing agent, a swelling agent, a swell-controlling agent and a gas generating material has advantages in that it maintains a constant cilostazol level in the blood through a slow release while it resides in the stomach and intestines over a long period of time, thereby increasing the absorption of cilostazol in the small intestine, the major absorption site of cilostazol, as well as minimizing adverse effects caused by rapid release and making it easy for a patient to take the drug.
La présente invention concerne une formulation de cilostazole à libération contrôlée, et un procédé d'élaboration correspondant. La formulation à libération contrôlée de l'invention comprend du cilostazole ou l'un de ses sels pharmaceutiquement admis, un solubilisant, un agent gonflant, un agent contrôlant le gonflement, et un matériau générateur de gaz. Restant dans l'estomac et dans les intestins pendant une longue durée, cette formulation est intéressante en ce sa libération lente maintient un niveau constant de cilostazole dans le sang. Cela permet d'augmenter l'absorption du cilostazole dans l'intestin grêle qui en est le site principal, de réduire les effets secondaires imputables à la libération rapide, et de simplifier pour le patient la prise du médicament.
Bae Joon Ho
Bin Sung Ah
Jeon Do Yong
Lee Hyeok
Park Jin Woo
Amorepacific Corporation
Cassan Maclean
Pacific Pharmaceutical Co. Ltd.
LandOfFree
Controlled-release preparation containing cilostazol and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Controlled-release preparation containing cilostazol and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Controlled-release preparation containing cilostazol and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2001396