Controlled release tabletted medicine

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/30 (2006.01) A61K 9/22 (2006.01)

Patent

CA 2181391

A controlled release tablet formulation for gastro-intestinal administration is made with i) at least one medicinally active ingredient, ii) at least three core polymers, iii) at least one filler, iv) at least one binder. The core polymers are selected from the group consisting of copolymers of sucrose and epichlorohydrin having molecular weights of from 70 000 to 400 000, glucose polymers having molecular weights of from 10 000 to 300 000, polyethylene glycols having molecular weights of from 1000 to 100 000, polyvinyl alcohols having molecular weights of from 70 000 to 110 000, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl-methyl cellulose, hydroxypropyl-ethyl cellulose, sodium carboxymethyl cellulose, gelatine, starch, crosslinked starch, polyethyleneimine, methoxypolyethylene glycol, ethoxypolyethylene glycol, polyethylene oxide, polyoxyethylene, polyoxypropylene, block copolymers of polyoxyethylene and polyoxypropylene, polyoxyethylene X-lauryl ether wherein X is from 9 to 20, cellulose acetate, sodium alginate, N,N-diethylaminoacetate, polyvinyl pyrrolidone, polyoxyethylene sorbitan esters, lecithin, lysolecithin and phospholipids. The tablet is useful for a wide range of medicinally active compounds, including drugs, vitamins, enzymes, minerals and proteins.

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