Controlled release therapeutic system for liquid...

Details Controlled release therapeutic system for liquid... Controlled release therapeutic system for liquid...

A - Human Necessities

61

K

167/164, 167/220

A61K 9/54 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 9/50 (2006.01) A61K 31/52 (2006.01)

Patent

CA 1338569

A controlled release pharmaceutical dosage formulation comprising microgranules of an active substance, such as theophylline, ketorolac-trometamine and naproxene, having dimensions such as to be easily kept in suspension in a liquid medium; and a plurality of layers coating such microgranules for controlling the release of the active substance contained in the microgranules at a predetermined time, and at the same time maintaining the release characteristics stable for long periods of time. The coated microgranules can be provided in a ready-to-use liquid suspension or as a solid mixture which can be suspended in a liquid vehicle at the moment of usage. The liquid vehicle may contain an immediately available quantity of the active substance.

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