A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01)
Patent
CA 2735581
Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
La présente invention a pour objet des procédés et des compositions pour moduler les caractéristiques de libération et/ou de charge en médicament dagents bioactifs encapsulés dans des systèmes dadministration à base de polymère par lintermédiaire dune modification directe du point isoélectrique et/ou de la charge nette de lagent bioactif.
Ayoub Mimoun
Burton Kevin
Tice Thomas R.
Woehr Torsten
Fetherstonhaugh & Co.
Genzyme Corporation
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