C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2659437
The present invention provides methods of screening for agents that inhibit the activity or expression of one or more polypeptides that contribute to the suppression of osteogenesis. The invention also provides methods of inducing osteogenesis in a cell by administering to the cell an agent that inhibits one or more polypeptides that contribute to the suppression of osteogenesis.
La présente invention concerne des procédés de criblage destinés à identifier des agents qui inhibent l'activité ou l'expression d'un ou de plusieurs polypeptides participant à la suppression de l'ostéogenèse. L'invention concerne également des procédés permettant d'induire l'ostéogenèse dans une cellule par administration à la cellule d'un agent qui inhibe un ou plusieurs polypeptides participant à la suppression de l'ostéogenèse.
Ding Sheng
Zhao Yuanxiang
Fetherstonhaugh & Co.
The Scripps Research Institute
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