Controlling protein levels in eucaryotic organisms

Details Controlling protein levels in eucaryotic organisms Controlling protein levels in eucaryotic organisms

A - Human Necessities

61

K

A61K 38/00 (2006.01) C07K 14/00 (2006.01) C07K 14/16 (2006.01)

Patent

CA 2362560

The invention relates to novel compounds comprising a ubiquitination recognition element and a protein binding element. The invention also relates to the use of said compounds for modulating the level and/or activity of a target protein. The compounds are useful for the treatment of diseases such as infections, inflammatory conditions, cancer and genetic diseases. The compounds are also useful as insecticides and herbicides.

L'invention porte sur de nouveaux composés comprenant un élément de reconnaissance d'ubiquitination et un élément de liaison des protéines. Cette invention porte également sur l'utilisation de ces composés dans la modulation du taux et/ou de l'activité d'une protéine cible. Les composés sont utiles dans le traitement de maladies telles que des infections, des états inflammatoires, le cancer et les maladies génétiques. Ces composés sont également utiles comme insecticides et herbicides.

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