C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) C12P 21/06 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2463914
The subject invention a method for converting liver stem/progenitor cells to a pancreatic functional cell by transfecting said liver cells with a pancreatic development gene and/or by culturing with pancreatic differentiation factors. The resulting cells produce and secrete insulin protein in response to glucose stimulation.
La présente invention concerne un procédé pour transformer les cellules souches / progénitrices du foie en cellules fonctionnelles du pancréas, qui consiste à transfecter les cellules du foie avec un gène de développement du pancréas et/ou à cultiver des facteurs de différenciation du pancréas. Les cellules ainsi obtenues produisent et sécrètent la protéine d'insuline en réponse à la stimulation par le glucose.
Ixion Biotechnology Inc.
Sim & Mcburney
LandOfFree
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