Converting cox inhibition compounds that are not cox-2...

Details Converting cox inhibition compounds that are not cox-2... Converting cox inhibition compounds that are not cox-2...

C - Chemistry, Metallurgy

07

D

C07D 209/28 (2006.01) A61K 31/405 (2006.01) A61K 31/4155 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/497 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2358241

A method of altering specificity of cyclooxygenase-inhibiting compounds that have a COOH moiety by changing the various COOH containing compounds, such as indomethacin, into ester derivatives or into secondary amide derivatives.

L'invention concerne une méthode d'altération de la spécificité de composés d'inhibition de cyclo-oxygénases possédant une fraction COOH par changement de plusieurs composés contenant COOH, tels que l'indométhacine, en dérivés d'esters ou en dérivés d'amides secondaires.

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