Cool storage of cultured epithelial sheets

Details Cool storage of cultured epithelial sheets Cool storage of cultured epithelial sheets

A - Human Necessities

01

N

167/322, 167/325

A01N 1/02 (2006.01) A61L 26/00 (2006.01) A61L 27/60 (2006.01) A61K 35/12 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2011111

The viability of cohesive sheets of cultured epithelial cells such as keratinocytes used as wound dressings is maintained or improved by storage at a temperature within the range of 8°-25°C, preferably 13°-23°C, for periods greater than 8 hours, preferably up to 26 hours. This method and the resulting product permits a significant increase in the shipping radius of cultured dressings manufactured in a central facility, and increases flexibility in scheduling of shipments and surgical procedures.

La viabilité de membranes cohésives de cellules épithéliales cultivées, comme les kératinocytes utilisés comme pansements pour les blessures, est maintenue ou prolongée lorsqu'on les conserve à une température située entre 8 et 25 degrés C, et de préférence entre 13 et 23 degrés C, pour une période supérieure à 8 heures, de préférence jusqu'à 26 heures. Cette méthode et son résultat permettent d'accroître considérablement le rayon de livraison des pansements cultivés fabriqués dans une installation centrale, et permet d'établir avec plus de souplesse le calendrier des livraisons et des interventions chirurgicales..

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