C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 69/10 (2006.01) A01N 25/10 (2006.01) A23L 1/30 (2006.01) A61K 8/88 (2006.01) A61K 47/34 (2006.01)
Patent
CA 2596147
The invention relates to novel biodegradable materials which are based on modified polyamino acids and which can be used for the vectorisation of active principle(s) (AP). The invention also relates to novel pharmaceutical, cosmetic, dietary or phytosanitary compositions based on said polyamino acids. The aim of the invention is to provide a novel polymer raw material which can be used for the vectorisation of active principles and which can optimally fulfil all required specifications in said area, namely: biocompatibility, biodegradability and the ability to become easily associated with many active principles or to solubilise said principles and to release same in vivo. Said aim is achieved with novel copolyhydroxyalkylglutamines comprising glutamine units and optionally glutamate units and bearing hydrophobic groups containing between 8 and 30 carbon atoms. Said copolyhydroxyalkylglutamines are amphiphilic and can be easily and economically transformed into particles for the vectorisation of active principles, whereby said particles can form stable aqueous colloidal suspensions.
La présente invention concerne des nouveaux matériaux à base de polyaminoacides modifiés, biodégradables, utiles notamment pour la vectorisation de principe(s) actif(s) (PA). L'invention vise aussi de nouvelles compositions pharmaceutiques, cosmétiques, diététiques ou phytosanitaires à base de ces polyaminoacides. Le but de l'invention est de fournir une nouvelle matière première polymère, susceptible d'être utilisée pour la vectorisation de PA et permettant de satisfaire de manière optimale à toutes les spécifications requises en l'espèce : biocompatibilité, biodégradabilité, aptitude à s'associer facilement avec de nombreux principes actifs ou à les solubiliser, et à libérer ces principes actifs in vivo. Ce but est atteint par la présente invention qui concerne des nouveaux copolyhydroxyalkylglutamines, comprenant des unités glutamines et éventuellement des unités glutamates, et qui sont porteuses de groupements hydrophobes comportant de 8 à 30 atomes de carbone. Ces copolyhydroxyalkylglutamines sont amphiphiles et sont aptes à se transformer aisément et économiquement en particules de vectorisation de principes actifs, ces particules étant elles même propres à former des suspensions colloïdales aqueuses stables.
Chan You-Ping
Soula Remi
Flamel Technologies
Goudreau Gage Dubuc
LandOfFree
Copolyhydroxyalkylglutamines which are functionalised with... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Copolyhydroxyalkylglutamines which are functionalised with..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Copolyhydroxyalkylglutamines which are functionalised with... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1946367