Copper-mediated oximation reaction

Details Copper-mediated oximation reaction Copper-mediated oximation reaction

C - Chemistry, Metallurgy

07

D

260/102, 260/302

C07D 417/12 (2006.01) C07D 499/70 (2006.01) C07D 501/20 (2006.01)

Patent

CA 1268759

GC239 COPPER-MEDIATED OXIMATION REACTION ABSTRACT The presence of a copper salt during the oximation of a .beta.-lactam containing compound having glyoxylamino substituents of the formula Image by reaction with an aminooxy compound having the formula H2N-O-Ra or a salt or ester thereof, results in a product wherein the ratio of syn isomer to anti isomer is increased.

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