Core formulation comprising troglitazone and a biguanide

Details Core formulation comprising troglitazone and a biguanide Core formulation comprising troglitazone and a biguanide

A - Human Necessities

61

K

A61K 9/24 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/30 (2006.01) A61K 9/32 (2006.01) A61K 9/34 (2006.01) A61K 9/38 (2006.01) A61K 9/40 (2006.01) A61K 9/50 (2006.01) A61K 9/58 (2006.01) A61K 9/60 (2006.01) A61K 9/62 (2006.01) A61K 9/64 (2006.01) A61K 31/155 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 47/04 (2006.01) A61K 47/34 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2453782

This invention relates to a controlled release combination drug product comprising troglitazone, e.g. its hydrochloride, and a biguamide, e.g. metformin. In particular, the product comprises a core of metformin, at least a portion thereof has a layer or coat thereon of troglitazone.

L'invention concerne un produit pharmaceutique combiné à libération contrôlée, notamment son chlorhydrate, et un biguamide, tel que la metformine. Le produit de l'invention contient plus particulièrement un noyau de metformine dont au moins une partie possède une couche de troglitazone.

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