Core/shell nanoparticles suitable for (f)ret-assays

Details Core/shell nanoparticles suitable for (f)ret-assays Core/shell nanoparticles suitable for (f)ret-assays

C - Chemistry, Metallurgy

09

K

C09K 11/02 (2006.01) C09K 11/81 (2006.01)

Patent

CA 2523027

The present invention relates to luminescent inorganic nanoparticles comprising (a) a core made from a first metal salt or oxide being surrounded by (b) a shell made from a second metal salt or oxide being luminescent and having non-semiconductor properties. These particles can be advantageously used in (fluorescence) resonance energy transfer ((F)RET)-based bioassays in view of their higher (F)RET efficiency.

L'invention concerne des nanoparticules luminescentes inorganiques comprenant (a) un noyau conçu à partir d'un premier sel ou oxyde métallique et entouré de (b) une enveloppe conçue à partir d'un second sel ou oxyde métallique, luminescente et ne possédant aucune propriété semi-conductrice. Ces particules présentent un caractère avantageux en ce qu'elles peuvent être utilisées dans des bio-essais fondés sur le transfert d'énergie par résonance (de fluorescence) ((F)RET), aux fins d'obtention d'un rendement supérieur du (F)RET.

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