Corpuscles of stannius protein, stanniocalcin

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/16 (2006.01) A61K 31/70 (2006.01) A61K 38/22 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 14/575 (2006.01) C07K 16/26 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2184905

There is disclosed a human Corpuscles of Stannius, stanniocalcin polypeptide and DNA (RNA) encoding such polypeptide. There is also provided a procedure for producing such polypeptide by recombinant techniques and for producing antibodies and antagonist/inhibitors against such polypeptide. Another aspect of the invention provides a combination of the polypeptide of the present invention and a suitable pharmaceutical carrier for providing therapeutic treatment of disease or the inhibition of such polypeptide for therapeutic treatment of disease.

L'invention concerne un polypeptide de stanniocalcine humaine des Corpuscules de Stannius et un ADN (ARN) codant pour ledit polypeptide. L'invention porte sur un mode opératoire pour produire ledit polypeptide par des techniques de recombinaison et pour produire des anticorps et des antagonistes/anticorps contre ledit polypeptide. Un autre aspect de l'invention concerne une combinaison du polypeptide décrit et d'un excipient pharmaceutique approprié pour le traitement thérapeutique de maladies ou pour l'inhibition dudit polypeptide à ces mêmes fins.

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