C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2479446
The present invention is directed to a method for determining whether a patient suffering from cancer is susceptable to a treatment with a 5-Fluoro-Uracil analogon comprising a) determination of Thymidine Phosphorylase mRNA expression in a clinical sample, b) determination of Dihydropyrimindine Dehydrogenase mRNA expression in said clinical sample, and c) determination of the ratio of the value obtained in step a) and the value obtained in step b). If the ratio exceeds a certain cut off, susceptability to 5-FU and/or 5-FU analoga can be expected.
Krause Friedemann
Lassmann Silke
Lutz Verena
Poignee Manuela
Porstmann Baerbel
F.hoffmann-La Roche Ag
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Correlation of the ratio of tp and dpd mrna expression... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Correlation of the ratio of tp and dpd mrna expression..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Correlation of the ratio of tp and dpd mrna expression... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1879823