C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/74 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 45/06 (2006.01) A61P 43/00 (2006.01) C07D 213/643 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01) C07D 213/80 (2006.01) C07D 213/82 (2006.01) C07D 213/85 (2006.01) C07D 213/87 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 239/48 (2006.01) C07D 401/04 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 417/12 (2006.01) C07D 471/
Patent
CA 2397633
Corticotropin-releasing factor (CRF) antagonists having the formulae (I), (II) or (III), wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes for preparing them. These compounds and their pharmaceutically acceptable salts are useful in the treatment disorders including CNS and stress-related disorders.
Cette invention concerne des antagonistes de la corticolibérine représentés par les formules (I) (II) ou (III) dans lesquelles les lignes en pointillé, A, B, Y, Z, G, R¿3?, R¿4?, R¿5?, R¿6?, R¿16? et R¿17? sont tels que définis dans le descriptif, ainsi que des procédés d'obtention de préparation desdits antagonistes. Ces composés ainsi que les sels acceptables au plan pharmaceutique de ces composés conviennent bien pour le traitement de certains troubles, notamment du système nerveux central, et des troubles liés au stress.
Pfizer Products Inc.
Smart & Biggar
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