Cortisone spray for topical administration

Details Cortisone spray for topical administration Cortisone spray for topical administration

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 9/107 (2006.01) A61K 9/12 (2006.01)

Patent

CA 2238263

The present invention relates to a pharmaceutical mixture for the dermal application of hydrocortisone. The active agent is dispersed with the addition of a partial fatty acid ester of polyoxyethylene sorbitan and other auxiliaries like lecithin and neutral oil. This provides a suspension of nanoparticles of the lipophilic agent hydrocortisone.

L'invention concerne une préparation pharmaceutique d'application dermique d'hydrocortisone. Ce principe actif est dispersé par adjonction d'un ester d'acide gras partiel de sorbitanne de polyéthylène et d'autres auxiliaires tels que la lécithine et l'huile neutre. Ce système permet d'obtenir une suspension de particules de l'ordre du nanomètre du principe actif hydrocortisone liphophile.

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