Cortistatin: neuropeptides, compositions and methods

Details Cortistatin: neuropeptides, compositions and methods Cortistatin: neuropeptides, compositions and methods

C - Chemistry, Metallurgy

12

N

C12N 15/16 (2006.01) A61K 38/22 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 14/575 (2006.01) C07K 16/26 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2254783

The present invention relates generally to nucleic acids encoding a neuropeptide designated cortistatin. The cortistatin nucleic acids, proteins and polypeptides thereof along with anti-cortistatin antibodies are useful in both screening methods, diagnostic methods and therapeutic methods related to modulation of sleep and disorders thereof.

La présente invention se rapporte, d'une manière générale, à des acides nucléiques codant un neuropeptide appelé cortistatine. Les acides nucléiques de la cortistatine, ses protéines et ses polypeptides ainsi que les anticorps anti-cortistatine sont utiles tant dans des méthodes de recherche que dans des méthodes du diagnostic ou dans des méthodes thérapeutiques liées à la modulation du sommeil et des troubles du sommeil.

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