C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/34 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 9/18 (2006.01) C12N 15/55 (2006.01) C12P 13/08 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2383875
Isolated nucleic acid molecules, designated SMP nucleic acid molecules, which encode novel SMP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SMP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SMP proteins, mutated SMP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SMP genes in this organism.
Cette invention concerne des molécules d'acides nucléiques isolées, dites molécules d'acides nucléiques SMP, qui codent pour de nouvelles protéines SMP tirées de Corynebacterium glutamicum. L'invention concerne également des molécules d'acides nucléiques antisens, des vecteurs d'expression recombinante renfermant des molécules d'acides nucléiques SMP et des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits. De plus, l'invention concerne des protéines SMP isolées, des protéines SMP mutées, des protéines de fusion, des peptides antigéniques, ainsi que des procédés qui permettent d'améliorer la production d'un composé recherché à partir de C. glutamicum en fonction du génie génétique de gènes SMP dans cet organisme.
Haberhauer Gregor
Kroger Burkhard
Pompejus Markus
Schroder Hartwig
Zelder Oskar
Basf Aktiengesellschaft
Borden Ladner Gervais Llp
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