C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/34 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 15/52 (2006.01) C12P 1/04 (2006.01) C12P 13/04 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2380870
Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.
L'invention porte sur des molécules d'acide nucléique isolées, appelées molécules d'acide nucléique SRT qui codent de nouvelles protéines SRT issues de Corynebacterium glutamicum. L'invention porte également sur des molécules d'acide nucléique antisens, sur des vecteurs d'expression de recombinaison contenant les molécules d'acide nucléique SRT, et sur des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits. L'invention porte encore sur des protéines SRT isolées, des protéines SRT mutées, des protéines de fusion, des peptides antigéniques et sur des procédés visant à accroître la production d'un composé désiré issu de C. glutamicum par manipulation des gènes SRT dans cet organisme.
Haberhauer Gregor
Kim Hyung-Joon
Kroger Burkhard
Lee Heung-Shick
Pompejus Markus
Basf Aktiengesellschaft
Borden Ladner Gervais Llp
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