Coryneform bacteria which produce chemical compounds ii

Details Coryneform bacteria which produce chemical compounds ii Coryneform bacteria which produce chemical compounds ii

C - Chemistry, Metallurgy

12

N

C12N 15/77 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 15/63 (2006.01) C12P 13/04 (2006.01) C12P 13/08 (2006.01)

Patent

CA 2456416

The invention relates to coryneform bacteria, which instead of the singular copy of an open reading frame (ORF), gene or allele naturally present at the particular desired site (locus), have at least two copies of the open reading frame (ORF), gene or allele in question, preferably in tandem arrangement, and optionally at least a third copy of the open reading frame (ORF), gene or allele in question at a further gene site, and processes for the preparation of chemical compounds by fermentation of these bacteria.

Cette invention concerne des bactéries coryneformes qui, au lieu d'une seule copie de cadre de lecture ouvert, de gène ou d'allèle naturellement présents dans un site particulier (locus) recherché, possèdent au moins deux copies du cadre de lecture ouvert, gène ou allèle en question, agencées de préférence en tandem, voire au moins une troisième copie desdits cadre de lecture ouvert, gène ou allèle dans un autre site de gène. L'invention concerne également des méthodes de préparation de composés chimiques par fermentation de ces bactéries.

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