A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/37 (2006.01) A61Q 7/00 (2006.01)
Patent
CA 2067923
ABSTRACT OF THE DISCLOSURE Triesters of citric acid are used for inducing, maintaining or increasing hair growth. Compositions for topical application to mammalian hair or scalp comprise: an effective amount of from 1% to 99% by weight of an ester of citric acid having the structure (1): Image (1) where R1, R2 and R3 each independently represent a branched or unbranched alkyl, alkenyl, aryl, alkylaryl or arylalkyl group, each said group having from 1 to 18 carbon atoms, R' represents -H, or a branched or unbranched saturated or unsaturated acyl, alkyl, aryl, alkylaryl or aylalkyl group having from 1 to 18 carbon atoms, in the presence of a cosmetically acceptable vehicle for the citric acid ester and in the absence of solid absorbent for the ester; said effective amount of said ester being sufficient to increase hair growth in the rat, when said composition is applied topically thereto over a period of no more than three months, by at least 10% more than that obtainable using a control composition from which the said ester has been omitted, in accordance with the Rat Hair Growth Test.
Natraj Collur Visweswaria
Raman Govindarajan
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Plc Unilever
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