Cosmetic composition for stimulating the synthesis of...

A - Human Necessities – 61 – K

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A61K 8/64 (2006.01) A61Q 19/08 (2006.01) C07K 5/00 (2006.01)

Patent

CA 2650578

Cosmetic composition which can be applied topically, comprising at least one compound of the general formula (I) in which R1 is H, C1-C20-alkyl, cycloalkyl or aryl-C1-C4-alkyl, n is 1-4, X is -O-, -NH- or -NR2- and R2 H or C1-C20-alkyl; and at least one compound corresponding to the above formula (I) but in which XR1 with X having the possible meaning of -NH- is the residue of an alpha-amino acid; use of these compounds and of the composition for stimulating the synthesis of the proteins of the basement membrane; and also both those compounds of the formula (I) in which X is -NR2- and both R1 and R2 are different from H, and the compounds corresponding to formula (I) but in which XR1 with X having the possible meaning of -NH- is the residue of an alpha-amino acid, as such.

L'invention concerne une composition cosmétique à usage local contenant au moins un composé de formule générale (I), dans laquelle R1 représente l'hydrogène, un alkyle en C1 à C20, un cycloalkyle ou un arylalkyle en C1 à C4, n vaut de 1 à 4, X est un groupe -O-, -NH- ou -NR2- et R2 représente l'hydrogène ou un alkyle en C1 à C20 ; ainsi qu'au moins un composé correspondant à la formule (I) ci-dessus, dans laquelle toutefois XR1 représente le reste d'un alpha-aminoacide lorsque X a la signification -NH- ; l'utilisation de ces composés et de la composition pour stimuler la synthèse des protéines de la membrane basale ; ainsi que les composés de formule (I), dans laquelle X est -NR2- et R1 de même que R2 sont autres que l'hydrogène, et les composés de formule (I), dans laquelle toutefois XR1 représente le reste d'un alpha-aminoacide lorsque X a la signification -NH-, eux-mêmes.

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